Every Orthodox Christian must offer due and fitting honor, love and obedience to the Ever-Virgin Mary and Queen of Heaven. Our Panagia prays unceasingly for our salvation and the salvation of all people.
The following prayer was composed by Patriarch Gennadios Scholarios of Constantinople
O Blessed Virgin, You are full of grace and among women the Most Blessed of any person; You are the adornment of the human race, the miracle of Angels, the joy of all creation, the crown of virtue, the most true image and likeness of God, the most well-disposed Queen, and we laud and praise your holiness. After all the glory we render to the Eternal Logos (Word) of God, our Creator and Savior, we directly confess and witness to your graces, O Theotokos, for You co-operated with and participated in the plan of our salvation. We beseech You, Most Holy Mother of God, accept also now our petition and send it for a favorable consideration to our Savior, and your Son, Jesus Christ, and through Him to the Unoriginate God and Father and the Holy Spirit. For you have served God in the very best of all the divine acts and in the greatest heavenly plan for the salvation of us humans. If God listens to sinners when they return in repentance to His obedience and love–O what supernatural wonder!–how will He reject your intercession on our behalf? We admit that we are sinful and unworthy of any heavenly or earthly visitation; and yet we dare to be bold because we know the depth of your own loving kindness and compassion that resembles that of God Himself. We also confess and witness to your own abiding favor and providence toward our nation, which has been demonstrated from the beginning until now.
For these reasons therefore do not overlook us, the least of your servants, but intercede on our behalf; show your guardianship over us. Our life is passing away and the guilt for our sins is great and heavy. Our repentance is lukewarm and uncertain. We turn to God Our Creator in repentance and immediately we return again to evil.
For this reason then, Most Compassionate Mother of Our Merciful Lord and Savior Jesus Christ, be quick to deliver us from these present fears of ours. Grant us a repentance that is as true and steadfast as possible; make us all to be diligent in the work of our salvation; supplement with your divine love for mankind what is lacking in us because of our natural weakness and long-standing companionship with evil. Dissolve the guilt of our many great sins, by generating a profound contrition in our soul and by offering it as a start to the divine love for mankind, through which so many repentant thieves, prostitutes, and publicans have been saved. If, through your own concern and effort on our behalf, we do not see the Light of Divine mercy shine upon us who are most imprudent and reckless, then all of our affairs will be filled with horrible fears and destruction. We know and are certain that you will not abandon us altogether; we still have hope that is based upon the abundance of God’s loving kindness toward mankind and your own many visitations to us. O Most Holy Theotokos, full of grace and Most Blessed among women, the Lord is indeed with you, and may He be also with us through you, now and ever and unto ages of ages. Amen.
(Source: A Prayer Book. An Anthology of Orthodox Prayers by Fr. Peter A. Chamberas)